Alkylsuccinylated oxidized cellulose-based amphiphiles as a novel multi-purpose ingredient for stabilizing O/W emulsions

A novel type of emulsifiers (STOC- SAC0, SAC8 & SAC12) were synthesized from nature-abundant cellulose by a two-step process: preparartion soluble TEMPO-mediated oxidation cellulosic nanocrystal and fractionation (STOC), introduction hydrophobic moiety alkyl (C0, C8 C12)succinylation resulting polysaccharides. The synthetic products structurally verified Fourier Transform Infrared (FT-IR), Nuclear Magnetic Resonance (NMR) Gel Permeation Chromatography (GPC). surface-active property functionality the new ingredients characterized determinations contact angle, ABTS radical scavenging Ferrous chelating ability, their performance as ingredient; which demonstrated that alkylsuccinylated TEMPO-oxidized celluloses (STOC-SACx) have unique multi-purpose functionalities: emulsifying, stabilizing antioxidant property. STOC-SAC12 displayed best surface activity with lowest angle (18° on basis) highest properties (compared to succinylated (C-SAC0) Fe2+ are significantly higher 10-fold 4.5-fold, respectively); accordingly also resulted in most stable homogeneous fish oil-in-water nanoemulsion mean droplet size 200 nm, polydispersity index 0.18 ζ-potential up −90 mV; evidenced scanning electron microscopy (SEM) confocal laser (CLFM) dynamic light scattering analyses. In short this work reported industry-feasible fully scalable approach transform abundant renewable plant into fucntionalities could find potential application delivery oxidation-prone bioactives through complicated emulsion systems.